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Central & Nephrogenic Diabetes Insipidus
Causes of central diabetes insipidus:
1-Head trauma
2-Post-surgical (hypophysectomy)
3-Tumors
* craniopharyngioma
* pinealoma
* meningioma
* germinoma
* leukemia/lymphoma
* metastatic tumors
4-Infections
* tuberculosis
* syphilis
* mycosis
* toxoplasmosis
* encepahlitis
* basilar meningitis
5-Granulomatous disesases
* sarcoidosis
* histiocytosis
* Wegeners' granulomatosis
6-Cerebrovascular diseases
* aneurysms
* cavernous sinus thrombosis
* Sheehan's syndrome (pospartum pituatry infarction)
* CVA
7-Idiopathic
Causes of nephrogenic diabetes insipidus:
1-Congenital
2-Medications
* lithium
* demecyclocine
* amphotericin B
* methoxyflurane
* colchicine
* vinblastine
* aminoglycosides
* cisplatin
3-Obstructive uropathy - during relief of obstruction
4-Chronic tubulo-interstitial kidney diseases
* analgesic nephropathy
* sickle cell nephropathy
* multiple myeloma
* amyloidosis
* sarcoidosis
* Sjogrens disease
* autoimmune/lupus
* polycystic kidney disease
* medullary cystic disease
5-Electrolyte disorders
* hypercalcemia
* potassium depletion
1-Head trauma
2-Post-surgical (hypophysectomy)
3-Tumors
* craniopharyngioma
* pinealoma
* meningioma
* germinoma
* leukemia/lymphoma
* metastatic tumors
4-Infections
* tuberculosis
* syphilis
* mycosis
* toxoplasmosis
* encepahlitis
* basilar meningitis
5-Granulomatous disesases
* sarcoidosis
* histiocytosis
* Wegeners' granulomatosis
6-Cerebrovascular diseases
* aneurysms
* cavernous sinus thrombosis
* Sheehan's syndrome (pospartum pituatry infarction)
* CVA
7-Idiopathic
Causes of nephrogenic diabetes insipidus:
1-Congenital
2-Medications
* lithium
* demecyclocine
* amphotericin B
* methoxyflurane
* colchicine
* vinblastine
* aminoglycosides
* cisplatin
3-Obstructive uropathy - during relief of obstruction
4-Chronic tubulo-interstitial kidney diseases
* analgesic nephropathy
* sickle cell nephropathy
* multiple myeloma
* amyloidosis
* sarcoidosis
* Sjogrens disease
* autoimmune/lupus
* polycystic kidney disease
* medullary cystic disease
5-Electrolyte disorders
* hypercalcemia
* potassium depletion
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