This slide shows a Reed-Sternberg cell typical of the nodular sclerosing form of Hodgkin's lymphoma. This usually presents in adolescence and young adults as painless lymphadenopathy most commonly in the cervical nodes.
The other histological forms (Rye Classification:Classification of Hodgkin's disease according to lymphocyte predominance, nodular sclerosing, mixed cellularity, and lymphocyte depletion types. ) .
Nodular sclerosing Hodgkin's disease has the worst prognosis.
