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Showing posts with label ANDROLOGY. Show all posts
Showing posts with label ANDROLOGY. Show all posts
Treatment of choice for a case of secondary syphilis
A 20-year-old student has a macular rash, generalized lymphadenopathy, apthous ulcers, and gray-white plaques around the anal area. A dark-field examination demonstrates spirochetes. Which of the following is the treatment of choice for this patient?
- a.Penicillin
- b.Ceftriaxone
- c.Tetracycline
- d.Interferon alpha
- e.Erythromycin
The answer is a.
Penicillin is the drug of choice for secondary syphilis. A positive darkfield examination in this patient confirms the diagnosis."benzathine penicillin G 2.4 million units IM or aqueous procaine penicillin G 600,000 units IM daily for ten days-In Late latent (more than 2 years), and tertiary syphilis treatment is benzathine penicillin G 2.4 million units weekly for three weeks or aqueous procaine penicillin G 600,000 units daily for 15 days.".
Ceftriaxone and tetracycline are usually considered to be alternative therapies. Interferon alpha has been used in the treatment of condyloma acuminata, a lesion that can be mistaken for syphilitic condyloma.
Picture for Klinefelter syndrome
The patient in the picture presents with gynecomastia and infertility. On exam, he has small, firm testes. Which of the following is correct?
a.The patient is likely to have low levels of gonadotropins
b.The patient has Turner syndrome
c.His most likely karyotype is 47 XXY
d.The patient will have normal sperm count and testosterone level
in abnormal sexual development in a female.
a.The patient is likely to have low levels of gonadotropins
b.The patient has Turner syndrome
c.His most likely karyotype is 47 XXY
d.The patient will have normal sperm count and testosterone level
The answer is (c).
The picture of infertility,gynecomastia, and tall stature is consistent with Klinefelter syndrome and an XXY karyotype. The patient has abnormal gonadal development with hyalinized testes that result in low testosterone levels and elevated levels of gonadotropin. Turner syndrome refers to the 45 XO karyotype that resultsin abnormal sexual development in a female.
Male Reproductive System: Hormone Pathways
A lecture on the hormones that play a role in the male reproductive system, with emphasis on the hormonal pathways.
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